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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

This year, for the most hotly contested position-one at the Central Committee of the China Democratic League's reception office-there were about 10,000 competitors.
China purchased 141,000 industrial robots in 2017, up 58.1% year-on-year, but foreign brands accounted for nearly three quarters of that, showing that the gap is still widening between Chinese robot makers and their foreign peers.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

中国投资10亿美金用以将进一步打造C9大学(中国最好的9所大学)。 经费将会主要用来吸引顶级的教职人员,建造世界一流的教学设施,和招募一流的声源。中国将会国际智力、教育和技能的人才大战中逐鹿。
10. Computer systems analyst

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

即使他们打的比赛也许并不完美,但是,金州勇士队完美的赛季开局阶段仍然在继续。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 东莞治理工业“二房东”
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

The soaring prices of 2008, when oil reached more than $140 a barrel, will repeat, though not likely in 2014, Mr. Hummel said. The price 'is going to go higher.'

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

与IBM合作,将iPad和iPhone销售给大企业客户,只是苹果在库克领导下打破自身藩篱的一个例子,而这是乔布斯一直不愿做的。
The developer behind Kinect Disneyland Adventures and Elite: Dangerous is taking the theme park business to the extreme in ScreamRide. The game lets players build outrageous roller coasters, thrill rides and attractions from the ground up and then take them for a test run. The game offers three ways to play: Engineers can construct elaborate rides that test the boundaries of physics and g-forces; Scream Riders get on these rides and experience the thrills and spills first-hand – sometimes resulting in untimely deaths; and Demolition Experts can use any means necessary to tear down an entire amusement park. With classic PC games like Roller Coaster Tycoon now playable on smartphones, this next generation of thrill-ride creator is a welcome interactive experience. It’s always fun to build, ride and destroy roller coasters – and ScreamRide offers plenty of ways to share the thrills with your friends.
雪莉·巴赛为007系列电影演唱了两首名曲,这是其中之一。从某种程度上来说,007系列电影一直讲述的是心愿达成的故事。观众在享受剧情的同时,耳旁听着最棒的歌手用强有力的声音唱着关于贪欲的歌词,真是恰到好处。所以无论你对这部电影抱有何种看法(尽管这不是007系列最佳电影之一),巴赛拥有上好的素材,创作了让人眼前一亮的歌曲。
当伊利诺伊大学的研究员着手建立一种靠嗅觉来鉴别化学物质的装置时,他们并不满足于提高人类鼻子的灵敏度。相反,他们发展出一种假鼻子,依靠对细菌的气味来鉴别和诊断某些疾病。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

This 1977 file photo shows Apple co-founder Steve Jobs as he introduces the new Apple II in Cupertino, Calif.
10月份,中国居民消费价格总水平(CPI)同比涨幅降至1.3%,为今年5月以来的最低涨幅;环比下降0.3%,为今年5月以来的首次环比下降。
您只需把杯子放到啤酒机上,杯底磁铁就会自动抬高,让啤酒流进杯子里。
尽管这笔节省下来的钱目前看来相当可观,但其实远不够填补随之而来的不断升高的患病率所增加的社会负担的窟窿。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

[k?n'tr?ul]

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

自2003年以来,上海软科教育信息咨询有限公司就根据第三方的数据,开始发布全球500强高校榜单。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

根据两位了解相关计划的人士的说法,中国政府正在禁止中国旅游团体赴韩国旅游,这是对韩国拟部署美制萨德(Thaad)反导系统的最新报复手段。
n. 补给,供给,供应,贮备

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

单词spontaneous 联想记忆:
不过,更大的尺寸将会对iOS 7和开发人员施加额外压力——后者必须找出方法,使自己的应用程序适用于更多配置规格。而另一方面,这些额外的规格也将为应用程序提供一些更为激动人心的机遇,我们应该能看到iOS 8将包含诸多可适应多屏幕规格的功能。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

7月,中国政府首次尝试规范互联网金融,央行、银监会、证监会等10家机构联合发布指导意见,提出了“互联网金融”的官方定义,并明确了各机构负责监管的互联网金融机构类型。
哦,对了,我刚刚说了勒布朗·詹姆斯这个夏天其实是自由球员吗?

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

population
尽管与普通的开瓶器并无二致,但它拥有精良的设计,是由不锈钢和实木制成的。
il不+legal合法的→不合法的
首先,我们来回顾一下这些南美国家吧。东道主巴西队肯定是第一个要提到的。时间倒流18个月,巴西在这段时间一直在努力,但是对人称“大菲尔”(Big Phil)的斯科拉里(Scolari)的任命起到了作用。他让球队重新拾回失去的信念。在2013年联合会杯决赛中,3:0大胜西班牙的战果让诸多专业人士震惊,也在突然之间,巴西让人们对他们寄予了厚望。虽然你无法驳斥这样的比分,但是我们依旧想知道巴西是否有实力赢得此次世界杯。人们预计,内马尔(Neymar)也将放出“魔法”大招,但是他们还是想依靠弗雷德来进球。这不是对弗雷德无礼,不过,在1994以及2002年,巴西之所以能够赢得世界杯还是依靠于罗纳尔多和罗马里奥领衔前线的成功,而这两位也被誉为世界杯的传奇人物。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

“We know the Netherlands and the Dutch from the Srebrenica massacre,” Mr Erdogan said, invoking the most shameful episode in modern Dutch history. “We know how rotten their character is from their massacre of 8,000 Bosnians there.”

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

n. [宗
第五步 帅到没朋友

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

近年来,大多数发达国家的排放量一直在逐步下降,这部分是因为不景气的经济形势,同时也是因为日益加强的气候政策。2013年,由28个国家组成的欧洲联盟(European Union)的排放量下降了1.8%,虽然德国和波兰等几个国家的耗煤量出现增加。英国、意大利和西班牙的排放量显著下降。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Winners: Raptors

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

IDC认为,中国人可支配收入的增加导致了消费的增加,从而推动了国内手机市场的快速增长。
D'ALOISIO HAS BEEN quoted opining that 'time is the new currency.' It's the driving notion behind Summly. It's also a strangely wise observation from a 17-year-old. At that age, many of us had more time on our hands than we knew how to fill without plummeting into severe boredom. It's easy to forget-conversing over lunch in a London caf钼 or strolling through the Tate Modern-that D'Aloisio was born in 1995 and has not yet graduated from high school. Or that he still lives in his childhood bedroom, in a cozy upper-middle-class home. As I chat with his parents, he excuses himself to work on his computer. Slouching down the hall in his stocking feet, hems of his skinny jeans brushing the hallway carpet, it is the most kidlike you will ever see him.
6.Gal Gadot
A lone European telephone bidder paid a top price of 9.1 million for a smaller 1825 version of John Constable’s admired but difficult-to-love 1824 vertical landscape, “The Lock,” that had been in the same British family since 1855.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

不要告诉我,你一定要得到这份工作,不然你就要失去你的房子,你的孩子会食不果腹,你的母亲得了癌症等等。公司不是慈善机构。
There are no right or wrong answers, just be honest with yourself.
只有科比在32岁的时候参加了更多的比赛,而且他的场均出场时间还少了几分钟,而且这还仅包括常规赛。
She has also performed on Jimmy Kimmel and The Ellen Show - not bad for someone who hasn't even hit adolescence.
Harry Styles, 'Harry Styles'

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

But the developments also point to the vast gap in the use of such cases between the US and EU, where a debate is under way over whether to grant China “market economy” status in the World Trade Organisation, a concession that would make it even harder to bring anti-dumping cases.
另一方面,10月份工业生产者出厂价格(PPI)连续第3个月同比下降5.9%。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The film version of the popular television series "Legend of Sword and Fairy", also known as Chinese Paladin starts shooting in Zhejiang Province today.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

'It's all bullshit. It's a lie. It's a Band-Aid lie to make them feel better. I know these people, I know they're lily-livered, and as long as it looks good on the surface, to them, that's enough.'

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

5. 范冰冰 1700万美元
Bedrooms are up a curving staircase. A loft-like library overlooks the central atrium. Walls of glass in the master suite and its en-suite bathroom take in acres of marshland. The suite opens to a sun deck on the water side of the house. Both other bedrooms also have en-suite bathrooms. The lower level is finished as a gym, with a half bath and a garage with space for several cars.
你说的有道理。那我们就把国王队归到“有可能”的那一档里吧。同样我会把掘金队也归到这一档,鉴于他们球队战绩相近,且都或放走或签约了某些功能失调的球员。奇才队也会被我归到这一档,到目前为止我还是不看好他们。
最令人兴奋地其实是交易期

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The fall in profits in December highlights the challenges facing an industrial sector racked by overcapacity and falling prices, adding to pressure on authorities to loosen monetary policy and boost infrastructure spending to cushion the slowdown.
Rank: 3
Dealers: Car dealers work toward reducing the paperwork involved in buying a car and the hours it takes to fill it out. That will give them more time to devote to upselling add-ons such as extended warranties, paint and fabric protection, and rust-proofing.
银行业

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Will Indian Prime Minister Narendra Modi try any more unorthodox economic experiments
这个交易对雷霆有诸多方面的意义:首先,吉布森可以短期内顶替受伤的埃内斯-坎特,而且他带来了季后赛经验、可靠的篮板球保障和坚实的防守——这些可能对阵马刺或火箭的季后赛时都是需要的。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

neglect
挪威诺贝尔和平奖委员会主席亚格兰赞扬这三位女士的成就,还说,除非女性享有和男性一样的机会,否则我们不能实现持久的和平。
Directing for a Comedy Series: Jill Soloway, “Transparent” (“Man on the Land”)
10月份,中国社会消费品零售总额增长放缓。另一方面,尽管上月出口走弱,中国规模以上工业增加值和全国固定资产投资增长仍大致保持平稳。
However, significantly fewer women (59 per cent) occupy positions as department heads or above than men (68 per cent) three years after graduation.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

内森是少数几位在夜间拍卖会上积极出价的交易商之一。他在佳士得的拍卖会上代表一位客户以50.65万英镑拍下了查尔斯-安东尼·夸佩尔(Charles-Antoine Coypel)1737年的画作《阿米达宫的毁灭》(The Destruction of the Palace of Armida),售价是预估价的两倍。
一个更大的侧影
Loyal employees of this auto services company are rewarded on their 10th anniversary -- and every five years after --with a weekend getaway at a resort in Boca Raton, Fla. (The company is headquartered just 15 minutes away.)

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

At the forum, tech entrepreneurs also shared their views on virtual reality, which they said will be the most important computing platform over the next five to 10 years.
14. 《与外婆同行》(Grandma),导演:保罗·韦兹(Paul Weitz)。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 深圳超八成租客租金收入比不到30%
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Episodic memory is also known as long-term memory, and the researchers approached the study of exercise in a different manner than previous studies. Other studies examined the impact of aerobic exercise conducted over many months, but this study simply asked participants to lift weights a single time. During the test, half of the participants were asked to use a weight machine before recalling a series of images they were shown at the start of the test. The other half of the participants were also asked to recall the images but without having engaged in any strenuous activity before the recall session. In demonstrating the memory improvement for the participants who engaged in just a single session of weight lifting, the researchers were able to show that improving one's memory through exercise didn't take hours of dedication in the gym. The next time you have the opportunity to lift weights or someone tries to convince you to join the gym you might just want to take him or her up on the offer.
"Poverty has stunted further growth in Internet users, which has kept the Net user population to around 50 percent," Li said.
The real Irving is named Mel Weinberg, and he and his mistress were in fact enlisted by the FBI to oust eight elected officials for taking bribes. Just like the film, Weinberg and the FBI developed an elaborate con to catch the corrupt politicians in the act. Weinberg did end up forming a friendship with one of the officials, although unlike in the film, his final immunity deal didn't protect the friend he helped implicate. Some things are just too far-fetched, even for a career criminal.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

adj. 不稳定的,易变的
多年以前,布莱恩·克兰斯顿还未在《绝命毒师》中饰演沃尔特·怀特,他曾和哥哥一起在一家餐馆打工。那儿的主厨是个非常刻薄的人。2011年,在马克·马龙的电台节目里当播客时,克兰斯顿如此描述道:"无论你对他多好,他还是讨厌你。"因此,所有的服务生平时都在谈论着如何谋杀他。克兰斯顿说这就是"他们平时讨论的所有内容"。
Local farmers must love this wireless company as much as its employees do. Once a week, San Diego-based Qualcomm hosts a farmers market at two of its locations. Items sold range from traditional produce to jams and jellies. Employees with CSA veggie box subscriptions can pick up their produce packages at one of the HQ's cafés.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Norway, which has twice rejected European Union membership, ranks No. 10 overall. The country takes the No. 1 spot in Citizenship and the No. 2 spot in Most Transparent.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

此次涵盖95个项目(去年为90个)的排行榜中,来自7个国家的9所院校为首次进入榜单。排名第41位的法兰克福金融管理学院(Frankfurt School of Finance & Management)是今年排名最高的新入榜者。这家德国学院拥有性别比例最平衡的项目之一,女性占学员总数的49%。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

On average, executive pay packets hit 7.09 million yuan in 2016, up 8% year-on-year, higher than the rate of China's GDP and per capita disposable incomes, which were 6.7% and 6.3% respectively.
“如果听到苹果CEO是同性恋,能帮助一些人努力直面自我,或者给一些感到孤独的人带来慰藉,或者激励人们坚持自己的平等权利,那么这值得我用个人隐私来交换,”他在为《彭博商业周刊》(Bloomberg Businessweek)的10月号撰文时写道。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 精装修“失宠”透视楼市变局
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

《寻梦环游记》
单词release 联想记忆:
Uruguay owes much of its success not just to its passion for football but also to the early inclusiveness of its culture. In that 1950 tournament, at a time when neighboring Brazil still regarded its black players with suspicion, Uruguay boasted a black captain, the brilliant Obdulio Varela. Moreover, Uruguay's victories in the World Cup's formative years established a pedigree that endures to this day, with many of its footballers -- such as Liverpool's Luis Suárez and Paris Saint-Germain's Edinson Cavani -- playing abroad for some of the world's biggest clubs.
9.微笑

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Bernard Baumohl 作为Economic Outlook Group的首席经济学家,表示他甚至更乐观的认为接下来的两年将会成为至少近十年以来形势最好的两年,他还称“有很多证据充分的表明了经济正在恢复的势头”。
1. Bottoms Up Beer System

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

If you are working your butt off and not getting paid enough to pay your bills, you might be overqualified and underpaid for your position. Go find a job that pays what you deserve.
当你和他/她在一起的时候,你看不见周围的所有人,你的眼中只有他/她

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 百安居瓷砖测算误差率高达37%
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

n. 谷物,小麦,玉米

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

斯蒂芬?韦格斯蒂尔(Stefan Wagstyl)柏林补充报道
2018年,将会有更多商业领袖利用数字化、代际变动和多元化不断提高的强大结合,来精简企业层级结构,分配责任,转变他们所在的组织。
Taylor Swift vs. Katy Perry
affected

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

strictly
2) I Trust Your Judgment: Translation: “You have my permission. I believe in you. Now, go make it happen.” Feels pretty uplifting to hear that, doesn’t it? And I’ll bet you’d do almost anything to please someone who makes you feel that way. Your employees and peers are no different.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The survey by the Public Religion Research Institute in partnership with the Religion News Service found political and religious disagreement on what is behind severe weather, which this year has included extreme heat and drought.
China has recently made majordecisions about its economic future. On November 15, 2013, China announceddramatic new social and economic policies contemplating much greater relianceon market forces than it has in the past and inviting private-sectorparticipation and foreign competition in industries long previously controlledby the central government. It also relaxed its one-child policy, openingthe country and its people to vast new opportunities and inspiring new hopes anddreams.
qualified

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 浙江特色小镇海外推广展走进巴黎
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

伦敦——在20世纪70年代,英国喜剧演员汤米·库珀(Tommy Cooper)讲过这样一个笑话:他在阁楼里发现一把小提琴和一幅画,让拍卖公司估价。拍卖公司说,好消息是它们分别出自斯特拉迪瓦里(Stradivarius)和伦勃朗(Rembrandt)之手。坏消息是那幅画是斯特拉迪瓦里画的,小提琴是伦勃朗做的。
3.You Spend More Time Surfing the Web Than Doing Your Job
单词appearance 联想记忆:

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

葡萄牙诺瓦商业与经济学院(Nova School of Business and Economics)巩固了去年的强劲表现,排名进一步攀升14个位置,排在了第17位。
今年年底10年期美国国债收益率会突破3%吗?

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 环保风暴过后 三亚6项目整改
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

7.助听器
adj. 在 ... 之前,先,前,以前的
外套。来一套贝达弗的大衣和蓝围巾。一套价值1350英镑的大衣,随时准备迎接人生的精彩时刻。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

EMBAGlobal is the only programme in the top 10 that saw a slight drop in the average salary of its alumni compared with last year (the other nine recorded strong increases).
Interviewers made their share of blunders, too.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Social scientists, after crunching data from both sides of the Atlantic, have discovered something surprising: it’s not the amount of racial or ethnic diversity in a community that predicts white resentment and support of anti-immigrant policies, but the pace of change.
Epic is not OK with ongoing cheating or copyright infringement from anyone at any age, it said.
intimidating

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

卓越雇主排名:32

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

《在生前留下的物品中回忆世界上最长寿的人》(Remembering the World’s Oldest Person, in the Objects She Left Behind)
Alternative fuels: For the first time since diesel-powered cars from Europe started arriving here in the 1950s, old first-person accounts about the joys of driving a diesel fall off to near zero. They are replaced by new first-person accounts about the joys of driving cars with ridiculously high horsepower like the 580-hp Chevrolet Camaro ZL1 and Dodge’s Challenger SRT Hellfire with 707 hp. Elsewhere: fuel-cell cars with their longer cruising range move center-stage, stealing the limelight from battery-powered cars.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The .40-calibre Smith & Wesson that killed her, a semi-automatic handgun, was seized by police to undergo ballistics testing to determine if it had been used in other crimes.
n. 身份,一致,特征

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 建材行业如何化解品牌难题
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

2013年日圆兑美元下跌21%,这为日本吸引来1,000万海外游客,尽管中日两国在东中国海(中国称东海)存在领土争端,然而这些游客中有许多是来自中国的富人。
排在榜单第三位的是31岁的克丽茜·泰根,她在过去的12个月里赚得1350万美金,首次跻身榜单。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

数年来,莎尔玛·海雅克和格温妮丝·帕特洛都是性侵的受害者,麦高恩表示,她明白特朗普的支持者都憎恨好莱坞,因为他们的自由主义都是假的。
2005年,戴维森发现自己总是得跟在一岁大的儿子杰克后面,收拾他随处乱扔的儿童吸管杯。于是,她从塔吉特(Target)上买了一台缝纫机,为儿童吸管杯设计出一个类似皮带的奇妙装置——SippiGrip。但她并没有很快实现自己的创业梦想——她加入了微软人力资源团队,与X-Box部门合作。2007年,她在全国性贸易展上推出了SippiGrip。幸运的是,塔吉特邀请她参加2008年父母发明产品计划。目前,戴维森的产品已经在沃尔玛(Walmart)、婴儿反斗城(Babies "R" Us)和亚马逊等零售商开卖。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Jackdaw Research的简?道森(Jan Dawson)表示,最近几个月“他表现得更加意气风发和充满自信”。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 东莞:二手房挂牌房源量增价降
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

China Hyundai dealers seek up to $135 million compensation
埃德加?赖特的《极盗车神》是本年度、十年内、甚至是本世纪最激动人心的飞车电影了。
"We have called the police and collected evidence to protect the company's reputation. Those who leaked the nude pictures will be punished according to law," the announcement read.
1.摄影:增长了22.3%

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

密码管理应用设计商Splashdata发布了一份“25个最常见密码” 榜单。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

The future is always bright if you are an entrepreneur, and the opportunities to create new ventures based on the digitisation of age-old services has a long way to run.
库尼斯在去年的榜单上排名第九。
国会将批准追加数十亿美元的刺激资金,但不会冠以“刺激”之名,也不会真正创造什么就业机会。国会将联合两党成立一个削减赤字的委员会,但同样发挥不了什么作用。既然美国国债还有投资者买,国会为什么要改弦更张?

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

自从2010年开通运营以来,12306票务系统已多次升级以修复漏洞,并在春运期间提供更好的服务。
STEP 9: BE SURE to tell everyone to shut up on a daily basis, it's endearing you know

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Meanwhile, villages within the city's boundaries will be overhauled and low-end manufacturers and logistics companies removed.
同时,罹患痛风的人升高了大约1/3,这个病在维多利亚时期的伦敦一度被视作“富贵病”,现在更倾向于认为与缺乏锻炼有关。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

1. Peaceful Era

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.
Homeowners in neighborhoods like the Grand Concourse in the Bronx or Elmhurst in Queens could enjoy new attention from buyers eager to find the next untapped market. “When have you heard talk about Kingsbridge in the Bronx?” asked Ms. Ramirez of Halstead. “The people who are smart are getting out there and buying it up at wonderful prices.”
张景岫说:“学生本身并不适合创业。”他补充说道,职业院校的学生比大学生更渴望自主创业。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

5.《出租车司机》
《国土安全》(Homeland):第三季末布洛迪(Brody,戴米恩·路易斯[Damian Lewis]饰)最终被杀后,映时频道(Showtime)的这部间谍惊悚剧似乎走到了尽头。目前看来,第四季没了他却变得充满活力,令人喜爱。卡莉(Carrie,克莱尔·丹尼斯[Claire Danes]饰)这次的对手是美貌、狡猾的巴基斯坦情报官塔斯尼姆(Tasneem,尼姆拉特·考尔[Nimrat Kaur]饰)。
adj. 突出的,显著的,未支付的
国家统计局表示,这一比例虽然与经济合作与发展组织成员国2.4%的平均水平还有差距,但已超过欧盟2.08%的平均水平。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

他还表示“包括现代汽车(Hyundai Motor)和爱茉莉太平洋(AmorePacific)在内,几乎每家韩国大企业都严重依赖对华销售。”
We need to ensure that our consumers will have access to good options, benefit from such consumption, and most importantly that Chinese companies will be able to win over the consumers with their commitment to high quality and workmanship.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

For all of the acceptance speech kerfuffle when Gwyneth Paltrow won best actress for her role as Viola de Lesseps in John Madden’s 1998 film Shakespeare in Love, the Hollywood star has since said she keeps the award tucked away – “the thing freaks me out”.
Nicolas Cage certainly bucks a lot of trends. He once told media that, for residency reasons, the award he won for the 1996 film Leaving Las Vegas was “in a truck somewhere moving through Louisiana”. Apparently, one of the ways the authorities determine if you’re a resident or not – in what must be the most niche of tests – is to ask where your Academy Award is.
7. Viceroy's House

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

This year, pop's best albums came from strong women who had a lot to say: Lorde's searing look at loneliness, Kesha's raucous statement of liberation, Taylor Swift's reckoning between her self and the version presented in the press.
这难道不是我们所有人都想要的吗?唐·德雷珀(Don Draper)应该会理解的。

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